The HIV virus mutates to resist gene editing attempts

When the going gets tough, the tough get going. This is only a temporary setback.

Gene editing sounds like a magic cure for all diseases, as it allows the tweaking and removal of genes that are deemed dangerous, or so one would tend to think. Unfortunately it is not all that simple.

Researchers have been struggling to cripple the HIV virus by cutting up its DNA by using a CRISPR, however, much to their amazement, they have discovered that the virus has not only survived that maiming but has also mutated to resist such incursions.

The problem is that the T cell of the host has helped the virus by repairing the cuts and inserting new DNA materials and thus creating a new mutated virus that the immune system can’t detect. This is a nightmare.

However, the good news is that, this setback is only temporary. There are techniques that could be used to beat the virus at its own game: by making multiple cuts, which deters the virus from further mutation, and by using anti-HIV drugs at the same time, the virus could be overwhelmed and defeated.

Although these gene editing techniques have so far no resulted in a complete cure, they do however suggests that HIV’s phenomenal adaptability, the key to its survival, is only a temporary hurdle. Furthermore, gene editing is a relatively new technology. As it matures, new solutions and procedures will increasingly be made to overcome such barriers.

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